After moving west and joining the famed Los Angeles Groundlings comedy improvisational troupe, Kathy began building her resume with guest starring roles on such series as "ER" and "Seinfeld" - where she created recurring character Sally Weaver.

After her various TV guest spots, Kathy began gaining notice as a stand-up comedienne and landed her own "HBO Half Hour Comedy Special." In 1998, HBO gave Kathy her own One-Hour Special, "A Hot Cup of Talk."

Kathy has co-hosted The Billboard Music Awards three years in a row; and appeared on numerous talk shows including "Late Night with David Letterman," "The Tonight Show with Jay Leno," "Howard Stern" and "The View," as well as having been featured in the films "It's Pat" and "Four Rooms" among others.

Kathy has performed two very successful stand-up specials for Bravo. The first in 2005 called "Kathy Griffin....Is Not Nicole Kidman" and the second in May of 2006 called "Strong Black Woman." Kathy's DVD stand-up special "Allegedly" is in stores now. In August 2005 Kathy's reality show, "Kathy Griffin: My Life On The D-List," debuted on Bravo to rave reviews. The second season of "Kathy Griffin: My Life On The D-List" has just been nominated for an Emmy for Outstanding Reality Program.