The first national Jersey Boys tour began on December 10, 2006 at the Curran Theatre in San Francisco. On May 3, 2007, that tour's run ended in San Francisco to prepare for its Los Angeles premiere at the Ahmanson Theatre. The next day, the second national tour debuted at the Curran and ended its run on September 30, 2007, before transferring for a long run at Chicago's LaSalle Bank Theatre through 2008. The second tour started in Chicago on October 5, 2007 with Chicagoan Michael Ingersoll in the role of Nick Massi. The national tour was promoted prominently by Broadway In Chicago and TheatreDreams who included it as part of their subscription series. The Chicago showing brought Frankie Valli and Bob Gaudio to Chicago for opening night and was promoted prominently, including a December 9, 2007 puck dropping at a Chicago Blackhawks game. Meanwhile the original US Tour continues to make its way across the country.

LaSalle Bank Theatre signA special holiday return engagement production played at the Curran from November 20 - December 30, 2007, starring Rick Faugno as Frankie Valli, Andrew Rannells as Bob Gaudio, Bryan McElroy as Tommy DeVito and Jeff Leibow as Nick Massi. The majority of this cast became the original Las Vegas cast, which will debuted at The Palazzo Hotel on Saturday, May 3. McElroy will assume the role of Tommy DeVito in the Chicago production in March, switching places with Jeremy Kushnier from the Chicago cast. Erich Bergen, from the first national tour, switched with Andrew Rannells.